Efficacy of Allium Sativum (Garlic) In the Treatment of Diabetes Induced In Laboratory Rats

  • Albert Olajumoke Modupe
  • Ajayi Johnson O.
  • Jolaoso Adeola A.
  • Jiboku Olukemi O.

Abstract

Diabetes has become one of the top killing metabolic disorders in which a person has high blood sugar either as a result of the pancreas not producing enough insulin (type I / Insulin Dependent Diabetes Mellitus [IDDM]) or the cells of the body not responding properly to the insulin produced (type II or Non Insulin Dependent diabetes Mellitus [NIDDM] or Adult Onset Diabetes). This research was centered on the induction of diabetes using Alloxan and subsequent treatment using Allium sativum (Garlic) extract (both fresh and aged). The result showed most of the Fasting Blood Sugar (FBS) being lowered from 68-50, 44-57, 51-47, in rat treated with diabetmin, 60-69, 51-72, 55-60 in rats treated with aged Garlic extract and 62-79, 67-76, 50-93 in rats treated with fresh Garlic extract and control given no treatment showing 74-160, 71-162, 49-138 all in milligram per deciliter (mg/dl) and weight reduction from 150-138, 138-125, 150-140 in rats treated with diabetmin , and weight increase from 138-160, 88-100 and 113-125 in rats treated with fresh garlic extract and weight reduction from 138-90, 137 – 90 and 100-97 (all weights are measured in grams) in rats that are not treated. The extracts of fresh and aged garlic show a promising ability in the management of diabetes.

International Journal of Research in Science, IJRS
Published
Dec 15, 2015
How to Cite
MODUPE, Albert Olajumoke et al. Efficacy of Allium Sativum (Garlic) In the Treatment of Diabetes Induced In Laboratory Rats. International Journal of Research in Science, [S.l.], v. 1, n. 3, p. 21-24, dec. 2015. ISSN 2412-4389. Available at: <https://www.researchplusjournal.com/index.php/IJRS/article/view/30>. Date accessed: 12 june 2026.
Citation Formats
Issue
Vol 1 No 3 (2015): International Journal of Research in Science
Section
Articles

Copyright & License

All Research Plus Journals (RPJ) publish open access articles under the terms of the Creative Commons Attribution (CC BY-SA 4.0) https://creativecommons.org/licenses/by-sa/4.0/ License which permits use, distribution and reproduction in any medium, provided the original work is properly cited & ShareAlike terms followed.

Copyright on any research article in a journal published by a RPJ is retained by the author(s). Authors grant RPJ a license to publish the article and identify itself as the original publisher. Upon author(s) by giving permission to RPJ either via RPJ journal portal or other channel to publish their research work in RPJ agrees to all the terms and conditions of https://creativecommons.org/licenses/by-sa/4.0/ License and terms & condition set by RPJ.

3rd party copyright

 It is the responsibility of author(s) to secure all necessary copyright permissions for the use of 3rd-party materials in their manuscript. 

Disclaimer

Research Plus Journals Open Access articles posted to repositories or websites are without warranty from RPJ of any kind, either express or implied, including, but not limited to, warranties of merchantability, fitness for a particular purpose, or non-infringement. To the fullest extent permitted by law RPJ disclaims all liability for any loss or damage arising out of, or in connection, with the use of or inability to use the content.